Daily sunscreen
In 903 adults in Queensland, Australia, those asked to use sunscreen every day showed no detectable increase in skin aging over 4.5 years, and 24% less aging than those who used it when they chose.
Randomized trial
Skin longevity, compared
Skincare, at-home light devices and supplements sold for aging skin: what's in each, what it costs, and how strong the evidence is. Ordered by price, never ranked for money.
16 products: skincare from longevity brands, ranges built around a longevity ingredient, sunscreens checked against our daily sunscreen check, and at-home LED devices, each with a US price and no current FDA warning letter or open recall on these products. How we choose.
Prices checked Oct 19–Nov 6, 202616 products · 6 categories · 2 supplement ingredients rated
All skin products
Grouped by type, then ordered by price, not ranked. Prices from each brand's own US store.
Buyer's guideLongevity skincare explained: evidence, cost and how many products you need16 of 16 shown · ordered by price, not ranked
Skincare ranges · 9
| Product | What's in it | Price | Published study | Link |
|---|---|---|---|---|
 Blueprint SkincareBryan Johnson's 3-step routineSerums & moisturizers · CleansersBlueprint supplements | SFC (disodium succinoyl farnesylcysteine), NMN, sodium hyaluronateCleanser 120 mL · serum 30 mL · moisturizer 50 mL | $39–$167Skincare Stack (all three) $167Checked Oct 31, 2026 | None cited | Visit site: Blueprint Skincare (opens in a new tab)Deep dive: Blueprint evidence |
 Niagen NanoCloudSachets you mix into your own serum or moisturizerSerums & moisturizersNR supplements | Niagen (nicotinamide riboside, NR), the NAD+ precursor in Tru Niagen's supplements30 or 60 sachets · NR amount per sachet not stated | $59–$9930 sachets $59, 60 sachets $99Checked Nov 6, 2026 | Brand's own 6-week survey37 women aged 35+, self-reported | Visit site: Niagen NanoCloud (opens in a new tab)Deep dive: NanoCloud evidence |
 Quicksilver Copper GHK+ serumCopper GHK+ Facial Serum with CycloastragenolSerums & moisturizers | GHK-Cu (copper tripeptide-1), cycloastragenol, bakuchiol, hyaluronic acid, vitamin C (tetrahexyldecyl ascorbate), vitamin E, tetrahydrocurcuminoids30 mL · amounts not stated | $59.5010% off on subscriptionChecked Nov 6, 2026 | None cited | Visit site: Quicksilver Copper GHK+ serum (opens in a new tab)Deep dive: Quicksilver evidence |
 Renue Blue skincareFace serum, face cream and body creamSerums & moisturizers · BodyRenue By Science supplements | NAD+, NMN and NR (Renue's liposomal "NAD+ Complex") with methylene blueSerum 50 mL · face cream 45 g · body cream 227 g · concentrations not stated | $65–$7210% off on subscriptionChecked Oct 31, 2026 | Brand's own 28-day user studies51 people (serum) and 38 (body cream), not published | Visit site: Renue Blue skincare (opens in a new tab)Deep dive: Renue Blue evidence |
 Aramore skincareTreatment, night cream, eye cream and retinol serumSerums & moisturizers · Eye care | NMN (an NAD+ precursor) in the treatment and eye cream, with ketones and fatty acids; the serum is 1% retinol with peptidesTreatment and cream 50 mL · retinol serum 30 mL · NMN amounts not stated | $76–$124Treatment and cream $110 each, eye cream $76, retinol serum $124Checked Nov 6, 2026 | Brand's own trials30 women, 8 weeks (treatment); 21 women, 12 weeks (cream); no comparison group described, not published | Visit site: Aramore skincare (opens in a new tab)Deep dive: Aramore evidence |
 Lancôme Absolue Longevity MDThree creams and two serums, split by ageSerums & moisturizersUrolithin A supplements | Mitopure (urolithin A, from Timeline), plus peptides, niacinamide or taurine depending on the product1.7 fl oz, some creams also 1.0 fl oz · Mitopure amount not stated | $110–$175Creams $155, serums $175, 1.0 fl oz creams $110Checked Nov 6, 2026 | Brand's own testsMethods not on the pages, and many figures are "up to" results. L’Oréal and Lancôme staff also co-wrote a 2026 urolithin A paper; not confirmed as these formulas | Visit site: Lancôme Absolue Longevity MD (opens in a new tab)Deep dive: Lancôme evidence |
 OneSkinOS-01 FACE moisturizerSerums & moisturizers · Cleansers · Eye care · Body | OS-01 peptide (Decapeptide-52), hyaluronic acid, niacinamide50 mL | $117$100 on subscriptionChecked Oct 31, 2026 | J Cosmet Dermatol, 202422 women, 12 weeks; authors include OneSkin scientists | Visit site: OneSkin (opens in a new tab)Deep dive: OneSkin evidence and routine |
 Timeline Mitopure skincareMitopure Firming SerumSerums & moisturizers · Cleansers · Eye careUrolithin A supplements | Mitopure (urolithin A), peptide complex, niacinamide, sodium hyaluronate30 mL · Mitopure amount not stated | $160Subscription price not statedChecked Oct 31, 2026 | iScience, 20261% urolithin A cream: 48 women, 8 weeks. Authors include Timeline, L’Oréal and Lancôme staff; not confirmed as this serum | Visit site: Timeline Mitopure skincare (opens in a new tab)Deep dive: Timeline evidence |
 Re-Q Pro-Longevity Face SerumFace serumSerums & moisturizers | RLX-201 (a patented TORC1 inhibitor, per the brand), turmeric root extract, a resveratrol-derived antioxidant, Swiss garden cress sprouts extract30 mL · amounts and full ingredient list not on the brand's site | $259$246.05 on subscriptionChecked Nov 6, 2026 | J Cosmet Dermatol, 202647 women randomized, 44 finished, 12 weeks; authors include Rapalogix's CEO and a co-founder | Visit site: Re-Q Pro-Longevity Face Serum (opens in a new tab)Deep dive: Re-Q evidence |
- Blueprint SkincareBryan Johnson's 3-step routine$39–$167
- What's in it
- SFC (disodium succinoyl farnesylcysteine), NMN, sodium hyaluronateCleanser 120 mL · serum 30 mL · moisturizer 50 mL
- Price
- Skincare Stack (all three) $167
- Published study
- None cited
- Categories
- Serums & moisturizers · Cleansers
Checked Oct 31, 2026Visit site: Blueprint Skincare (opens in a new tab)Deep dive: Blueprint evidence - Niagen NanoCloudSachets you mix into your own serum or moisturizer$59–$99
- What's in it
- Niagen (nicotinamide riboside, NR), the NAD+ precursor in Tru Niagen's supplements30 or 60 sachets · NR amount per sachet not stated
- Price
- 30 sachets $59, 60 sachets $99
- Published study
- Brand's own 6-week survey37 women aged 35+, self-reported
- Categories
- Serums & moisturizers
- Quicksilver Copper GHK+ serumCopper GHK+ Facial Serum with Cycloastragenol$59.50
- What's in it
- GHK-Cu (copper tripeptide-1), cycloastragenol, bakuchiol, hyaluronic acid, vitamin C (tetrahexyldecyl ascorbate), vitamin E, tetrahydrocurcuminoids30 mL · amounts not stated
- Price
- 10% off on subscription
- Published study
- None cited
- Categories
- Serums & moisturizers
- Renue Blue skincareFace serum, face cream and body cream$65–$72
- What's in it
- NAD+, NMN and NR (Renue's liposomal "NAD+ Complex") with methylene blueSerum 50 mL · face cream 45 g · body cream 227 g · concentrations not stated
- Price
- 10% off on subscription
- Published study
- Brand's own 28-day user studies51 people (serum) and 38 (body cream), not published
- Categories
- Serums & moisturizers · Body
- Aramore skincareTreatment, night cream, eye cream and retinol serum$76–$124
- What's in it
- NMN (an NAD+ precursor) in the treatment and eye cream, with ketones and fatty acids; the serum is 1% retinol with peptidesTreatment and cream 50 mL · retinol serum 30 mL · NMN amounts not stated
- Price
- Treatment and cream $110 each, eye cream $76, retinol serum $124
- Published study
- Brand's own trials30 women, 8 weeks (treatment); 21 women, 12 weeks (cream); no comparison group described, not published
- Categories
- Serums & moisturizers · Eye care
Checked Nov 6, 2026Visit site: Aramore skincare (opens in a new tab)Deep dive: Aramore evidence - Lancôme Absolue Longevity MDThree creams and two serums, split by age$110–$175
- What's in it
- Mitopure (urolithin A, from Timeline), plus peptides, niacinamide or taurine depending on the product1.7 fl oz, some creams also 1.0 fl oz · Mitopure amount not stated
- Price
- Creams $155, serums $175, 1.0 fl oz creams $110
- Published study
- Brand's own testsMethods not on the pages, and many figures are "up to" results. L’Oréal and Lancôme staff also co-wrote a 2026 urolithin A paper; not confirmed as these formulas
- Categories
- Serums & moisturizers
- OneSkinOS-01 FACE moisturizer$117
- What's in it
- OS-01 peptide (Decapeptide-52), hyaluronic acid, niacinamide50 mL
- Price
- $100 on subscription
- Published study
- J Cosmet Dermatol, 202422 women, 12 weeks; authors include OneSkin scientists
- Categories
- Serums & moisturizers · Cleansers · Eye care · Body
Checked Oct 31, 2026Visit site: OneSkin (opens in a new tab)Deep dive: OneSkin evidence and routine - Timeline Mitopure skincareMitopure Firming Serum$160
- What's in it
- Mitopure (urolithin A), peptide complex, niacinamide, sodium hyaluronate30 mL · Mitopure amount not stated
- Price
- Subscription price not stated
- Published study
- iScience, 20261% urolithin A cream: 48 women, 8 weeks. Authors include Timeline, L’Oréal and Lancôme staff; not confirmed as this serum
- Categories
- Serums & moisturizers · Cleansers · Eye care
- Re-Q Pro-Longevity Face SerumFace serum$259
- What's in it
- RLX-201 (a patented TORC1 inhibitor, per the brand), turmeric root extract, a resveratrol-derived antioxidant, Swiss garden cress sprouts extract30 mL · amounts and full ingredient list not on the brand's site
- Price
- $246.05 on subscription
- Published study
- J Cosmet Dermatol, 202647 women randomized, 44 finished, 12 weeks; authors include Rapalogix's CEO and a co-founder
- Categories
- Serums & moisturizers
Sunscreen that meets our daily check · 3 · broad spectrum, SPF 30+, water-resistant, actives published
| Product | What's in it | Price | Published study | Link |
|---|---|---|---|---|
 Sun Bum Original SPF 50 LotionBody sunscreenSunscreen | Avobenzone 3%, homosalate 10%, octisalate 5%, octocrylene 10%. Broad spectrum, water-resistant for up to 80 minutes. Contains fragrance3 oz to 16 oz | $11.49–$33.493 oz $11.49, 8 oz $18.99Checked Nov 6, 2026 | None of this productThe evidence is for daily sunscreen in general (Hughes, 2013) | Visit site: Sun Bum Original SPF 50 Lotion (opens in a new tab) |
 EltaMD UV Sport SPF 50+Full-body sunscreen for active useSunscreen | Zinc oxide 9%, octinoxate 7.5%, octisalate 5%. Broad spectrum, water-resistant for 80 minutes3 oz or 8 oz | $32–$623 oz $32, 8 oz $62Checked Nov 6, 2026 | None of this productThe evidence is for daily sunscreen in general (Hughes, 2013) | Visit site: EltaMD UV Sport SPF 50+ (opens in a new tab) |
 La Roche-Posay Anthelios Melt-In Milk SPF 60Sunscreen for face and bodySunscreen | Avobenzone 3%, homosalate 10%, octisalate 5%, octocrylene 7%. Broad spectrum, water-resistant for 80 minutes150 mL | $37.99Checked Nov 6, 2026 | None of this productThe evidence is for daily sunscreen in general (Hughes, 2013) | Visit site: La Roche-Posay Anthelios Melt-In Milk SPF 60 (opens in a new tab) |
- Sun Bum Original SPF 50 LotionBody sunscreen$11.49–$33.49
- What's in it
- Avobenzone 3%, homosalate 10%, octisalate 5%, octocrylene 10%. Broad spectrum, water-resistant for up to 80 minutes. Contains fragrance3 oz to 16 oz
- Price
- 3 oz $11.49, 8 oz $18.99
- Published study
- None of this productThe evidence is for daily sunscreen in general (Hughes, 2013)
- Categories
- Sunscreen
Checked Nov 6, 2026Visit site: Sun Bum Original SPF 50 Lotion (opens in a new tab) - EltaMD UV Sport SPF 50+Full-body sunscreen for active use$32–$62
- What's in it
- Zinc oxide 9%, octinoxate 7.5%, octisalate 5%. Broad spectrum, water-resistant for 80 minutes3 oz or 8 oz
- Price
- 3 oz $32, 8 oz $62
- Published study
- None of this productThe evidence is for daily sunscreen in general (Hughes, 2013)
- Categories
- Sunscreen
Checked Nov 6, 2026Visit site: EltaMD UV Sport SPF 50+ (opens in a new tab) - La Roche-Posay Anthelios Melt-In Milk SPF 60Sunscreen for face and body$37.99
- What's in it
- Avobenzone 3%, homosalate 10%, octisalate 5%, octocrylene 7%. Broad spectrum, water-resistant for 80 minutes150 mL
- Published study
- None of this productThe evidence is for daily sunscreen in general (Hughes, 2013)
- Categories
- Sunscreen
Longevity-brand SPF · 1 · doesn't meet the check
| Product | What's in it | Price | Published study | Link |
|---|---|---|---|---|
| OneSkin OS-01 FACE SPF 30Mineral face sunscreen with OS-01 peptideSunscreen | Zinc oxide 17.5%, plus the OS-01 peptide. Broad spectrum. Not water-resistant, per OneSkin40 mL | $56Checked Nov 6, 2026 | None found on the added peptideNo published trial of what the peptide adds to a sunscreen | Visit site: OneSkin OS-01 FACE SPF 30 (opens in a new tab) |
- OneSkin OS-01 FACE SPF 30Mineral face sunscreen with OS-01 peptide$56
- What's in it
- Zinc oxide 17.5%, plus the OS-01 peptide. Broad spectrum. Not water-resistant, per OneSkin40 mL
- Published study
- None found on the added peptideNo published trial of what the peptide adds to a sunscreen
- Categories
- Sunscreen
Checked Nov 6, 2026Visit site: OneSkin OS-01 FACE SPF 30 (opens in a new tab)
LED & light devices · 3 · also on Longevity products, Light therapy
| Product | What's in it | Price | Published study | Link |
|---|---|---|---|---|
 Renpho Artemis LED masksLED face masksLED & light devices | Red, blue and near-infrared LEDsArtemis II Aër FDA-cleared (510(k) K253712, model RB-061) | $159.99–$259Checked Oct 19, 2026 | No study published by the brand | Full card on Longevity products |
 HigherDOSE Red LightLED face mask, neck and body matLED & light devices | Red and near-infrared LEDsHigherDOSE says the face mask is FDA-cleared. A HigherDOSE mask (model MK66-L) is in the FDA database (K241933), but the page gives no model number to match. | $349–$1,199Checked Oct 19, 2026 | Brand's own 8-week trialdescribed by the brand as third-party | Full card on Longevity products |
 Therabody TheraFace MaskLED face masksLED & light devices | Red, near-infrared and blue LEDs plus vibration massageTheraFace Mask FDA-cleared (510(k) K230293). Mask Glo: Therabody says cleared; not found in the FDA database. | $379.99–$649.99Checked Oct 19, 2026 | Brand's own 12-week studies31 and 104 people | Full card on Longevity products |
- Renpho Artemis LED masksLED face masks$159.99–$259
- What's in it
- Red, blue and near-infrared LEDsArtemis II Aër FDA-cleared (510(k) K253712, model RB-061)
- Published study
- No study published by the brand
- Categories
- LED & light devices
Checked Oct 19, 2026Full card on Longevity products - HigherDOSE Red LightLED face mask, neck and body mat$349–$1,199
- What's in it
- Red and near-infrared LEDsHigherDOSE says the face mask is FDA-cleared. A HigherDOSE mask (model MK66-L) is in the FDA database (K241933), but the page gives no model number to match.
- Published study
- Brand's own 8-week trialdescribed by the brand as third-party
- Categories
- LED & light devices
Checked Oct 19, 2026Full card on Longevity products - Therabody TheraFace MaskLED face masks$379.99–$649.99
- What's in it
- Red, near-infrared and blue LEDs plus vibration massageTheraFace Mask FDA-cleared (510(k) K230293). Mask Glo: Therabody says cleared; not found in the FDA database.
- Published study
- Brand's own 12-week studies31 and 104 people
- Categories
- LED & light devices
Checked Oct 19, 2026Full card on Longevity products
Never ranked for money. No brand pays to be listed or for a better position. How we check.
What the evidence says
How strong the published research is for each kind of skin care, strongest first. This page lists products; it doesn't tell you what to use. A dermatologist can. For the studies in detail, read Longevity skincare explained.
Tretinoin (prescription)
Across 8 randomized trials and 1,361 people, tretinoin improved fine and coarse facial wrinkles compared with a base cream, over 16 weeks to 2 years. Some of the trials were company-funded, and it can irritate skin.
Review of randomized trials
Retinol
Retinol lotion smoothed fine wrinkles compared with a plain lotion over 24 weeks, in a small trial of 36 people with an average age of 87, tested on the arm.
Randomized trial
Red and near-infrared light
Small trials show modest changes in fine lines and firmness. Many are run or paid for by the device makers.
Small trials
New "longevity" actives: OS-01 peptide, SFC, topical NMN, NR and NAD+, urolithin A, RLX-201
Each rests on the company's own study, or none has been published. No long-term results yet.
Each brand's own site
Checked Nov 6, 2026
Supplements sold for skin
Rated on the same evidence tiers as every other supplement on the site.
Collagen peptides
Tier 2 · moderate evidenceRated on joints: trials in knee osteoarthritis found less pain, including one with no company funding. For skin, the trials not paid for by companies found no effect.
Meta-analysis of 23 trials on skin, Am J Med 2025
Read the evidence cardHyaluronic acid
Tier 3 · early evidenceSmall trials of the oral form suggest modest effects on skin moisture. One of the two main trials was run by a company that makes it.
Randomized trial, 40 adults, Nutrients 2021 (Kewpie)
Read the evidence cardStraight answers
Is anything on this page medical advice?
No. It describes what each product contains, what it costs and what has been published about it. It doesn't tell you what to use. For a skin concern, see a doctor or a dermatologist.
How do you decide what's listed, and how is it checked?
We list skincare sold for aging skin by longevity brands, ranges from other brands built around a named longevity ingredient, sunscreens checked against our daily sunscreen check, and at-home LED devices sold for skin, where the brand publishes a US price on its own store. Every price and fact was checked on the brand's own US site on the date shown. Where a brand doesn't say something (a concentration, a subscription price, who ran a study), we say so rather than guess. Products are grouped by type, then ordered by price. Spotted something that's changed? Tell us through the contact form.
Checked Oct 19–Nov 6, 2026Why don't you score each product?
Skincare brands rarely publish how much of each active a product contains, so a score would be a guess. We show the actives each brand names, and the study it cites, if any. The "What the evidence says" panel sums up how strong the published research is for each kind of active. Every product here rests on the brand's own studies, or none, and none of the 9 skincare ranges contains a sunscreen filter, the active with the strongest evidence.
Does any brand pay to be on this page?
No. No brand pays to be listed, and nothing a brand does can change its position. Products are grouped by type and ordered by price. How we check, and our disclosure.